EPCAM and hepatocellular carcinoma: Here are some examples: Scirrhous HCC has significantly reduced HepPar1 positivity compared to conventional HCC (26% vs. 74%) while frequently expressing adenocarcinoma-associated markers, including CK7 (53% vs. 2%), CK19 (26% vs. 2%), and epithelial cell adhesion molecule (EpCAM, 63% vs. 11%) [95].