Table 1 summarizes currently used diagnostic markers for HCC. Figure 1 illustrates representative HE stains of HCC tissue, accompanied by IHC staining patterns: (A) H&E HCC; (B) HepPar1; (C) Arginase; (D) glypican-3; (E) Poly-CEA; (F) CD10; (G) GS; (H) CD34; (I) albumin ISH; and (J) CD31. Figure 2 illustrates a visual flowchart outlining the IHC diagnostic pathway for HCC. The gene discussed is CD34; the disease is hepatocellular carcinoma.