These findings were corroborated in a study of CD10 IHC in 50 liver lesions (25 HCCs and 25 metastases) demonstrating a diagnostic sensitivity of 68% (17/25 HCC cases) and a specificity of 84%, with nonspecific cytoplasmic or membranous staining in four cases of metastatic carcinoma (one pancreatic primary, two gallbladder primary, and one of unknown primary) [71]. The gene discussed is MME; the disease is hepatocellular carcinoma.