The genes from which these circRNAs originate (COL15A1, DOCK7, ADAMTS5, HADH, COL3A1, TGFBR3, ISM1, ARL13B, POSTN, KCTD9, KRT77, SEMA3C, CTNND1, DKK3, ZNF114, and FTO) are involved in the HF growth process [38,39,40,41,42,43,44,45,46,47,48,49,50,51,52]. The gene discussed is ISM1; the disease is hydrops fetalis.