EGFR and hydrops fetalis: The results of GO functional annotation showed that the regulation of epidermis development (GO:0045682), HF development (GO:0001942), HF morphogenesis (GO:0031069), HF maturation (GO:0048820), Wnt signalling pathway (GO:0016055), skin morphogenesis (GO:0043589), SMAD protein signal transduction (GO:0060395), skin development (GO:0043588), regulation of Notch signalling pathway (GO:0008593), activation of MAPK activity (GO:0000187), keratin filament (GO:0045095), and epidermal growth factor receptor (GO:0005154) were significantly enriched (Figure 3).