Similarly, fermented figs rich in BT-LP-01 lactobacillus showed potential therapeutic effects on obesity and diabetes, and reduced the body weight, organ weight, fasting blood glucose, insulin/C-peptide levels, serum lipids, and expression of liver lipid synthesis-related genes (FAS, C/EBPα, FABP4) in obese mice in a dose-dependent manner [74]. Here, INS is linked to obesity due to melanocortin 4 receptor deficiency.