CDKN1A and type 2 diabetes mellitus: The qRT-PCR expression findings of these genes were consistent with the RNA-seq analysis (Figure 5k–o), showing four genes with increased expression (CD68, C1qa, C1qb, and CDKN1A) and one gene with decreased expression (Cyp2a5) in the HBP administration groups compared with the T2DM group.