BDNF and depressive disorder: From a clinical perspective, the presence of omega-3 (ALA, EPA, DHA) and omega-9 (oleic acid) fatty acids promotes synaptic plasticity, reduces inflammatory markers, and promotes an increase in BDNF (brain-derived neurotrophic factor) levels, which is particularly important in cases of depression, cognitive impairment, and schizophrenia spectrum disorders [119].