TP53 and acromegaly: Qiao et al. [86] interestingly applied AI to analyze pathological images (pathomics) for predicting outcomes in acromegaly patients after SRS and obtained a model which could predict endocrine remission with 92.9% accuracy, 87.5% sensitivity and 100% specificity, with proliferation (Ki-67), cellularity, granulation pattern and some immunohistochemistry markers (p53+, SSTR2A-) being the main pathomic features.