ROCK1 and cancer: Given the well-established roles of copper metabolism (mediated by chaperones such as ATOX1) and Rho/ROCK signalling in cancer pathogenesis, coupled with emerging evidence underscored by lung cancer models showing anti-tumour effects upon their inhibition, we aimed to comprehensively evaluate the expression profile, prognostic significance, and therapeutic potential of ATOX1 and ROCK1 in the context of LUAD.