We revealed herein that AA elicits distinct anti-proliferative effects on various human cancers (HepG2, Huh-7, LNCaP, DU-145, C4-2B, 22Rv1, MCF-7, MDA-MB-231, MDA-MB-453, and A549) and normal cell lines (Vero and RWPE1), which may be linked to the AR expression status of the cancer cell lines. The gene discussed is AR; the disease is cancer.