They found that on day 10 (D10) after CAR-T infusion, treated patients who presented with coagulopathy had higher levels of ANG-2 (6411 vs. 3944 pg/mL, p = 0.015) and increased ANG-2: ANG-1 ratio (6.25 vs. 3.30, p = 0.014) as compared to the rest of the patient cohort. The gene discussed is ANGPT2; the disease is blood coagulation disease.