IRF7 and colon carcinoma: Additionally, our RNA sequencing analysis of the publicly available dataset on in vivo TECs isolated from murine MC38 colon carcinomas irradiated with a single dose of 15 Gy showed consistent results, including the up-regulation of DNA-sensing pathways and the genes involved, such as Rig1, Irf7, Nf-κβ, and Il-6.