In addition, the pharmacological inhibition of LSD1 with SP2509 increased the serum level of several cytokines (IFNβ, IFNγ, IL-9), promoted the infiltration of tongue tumors with activated (CD4+, CD8+, CD45+) T cells, and reduced the percentage of immunosuppressive (CD25+) T cells in experimental mice [34]. Here, KDM1A is linked to tongue neoplasm.