EGFR and lung cancer: Molecular alterations in lung cancer have been identified in (i) growth factor receptors such as epidermal growth factor receptor (EGFR) and fibroblast growth factor receptor 1 (FGFR1), (ii) oncogenes including K-RAS, B-RAF, DDR2, and PIK3CA, and (iii) tumor suppressor genes such as p53, LKB1, and PTEN.