Oncogenic miRNAs (e.g., miR-9, miR-182, let-7c, and let-7g) were found to regulate a wide array of mRNA targets implicated in tumorigenesis (Figure 7), including NFKB1, CCDN1, DNMT1, PIK3C (A,B), RAF1, PTEN, BCL2, MET, ERBB2, and TP53, implicated in the initiation of urothelial tumorigenesis, patient prognosis, tumor progression, cell proliferation, and survival [48,54,65,66,67,68,69,70,71,72]. The gene discussed is RAF1; the disease is neoplasm.