Additionally, individual miRNAs were associated with unique pathways, including let-7c/ER protein processing, miR-9/serotonergic synapse, miR-182/TGF-β signaling, and miR-143/hypertrophic cardiomyopathy and rheumatoid arthritis, further supporting their diverse functional roles. The gene discussed is TGFB1; the disease is hypertrophic cardiomyopathy.