Madeddu et al. [55] further showed that IL-6 levels and miniCASCO-based cachexia severity were independent predictors of both PFS (HR = 1.04 and HR = 1.26) and OS (HR = 1.04 and HR = 2.38), supporting the prognostic role of inflammatory and nutritional alterations in cachexia. Here, IL6 is linked to Cachexia.