AKT1 and non-small cell lung carcinoma: As such, it is a simple aromatic aldehyde, and it has been shown in vitro to suppress multiple oncogenic signaling pathways, including PI3K/Akt/mTOR, NF-κB, STAT3, and ERK, by disrupting the 14-3-3-mediated protein interactions in pancreatic (BxPC-3) and non-small-cell lung cancer (A549) cell lines.