In vivo models of murine AML and analysis of primary samples from patients with AML revealed that the RNA-binding protein Y-box binding protein 1 (YBX1) affects the stability of m6A-enriched transcripts of apoptotic genes, such as Bcl2 and c-Myc, by interacting with IGF2BPs [84]. Here, YBX1 is linked to acute myeloid leukemia.