Furthermore, Han et al. [87] showed that METTL16 is essential for survival and stemness of the AML cells by regulating the branched-chain amino acid (BCAA) metabolic pathway and particularly the expression of branched-chain amino acid transaminases 1 and 2 (BCAT1 and BCAT2) [87]. Here, BCAT1 is linked to acute myeloid leukemia.