Additionally, using data from the Cancer Genome Atlas, it was found that 48% of pancreatic cancer patients had alterations in genes related to neuroactive molecules or their receptors, with the most notable change being in the neurotrophic receptor tyrosine kinase 1 (NTRK1) gene, which encodes TrkA [128]. Here, NTRK1 is linked to familial pancreatic carcinoma.