GJB1 and X-linked Charcot-Marie-Tooth disease type 1: Sargiannidou et al. and Kagiava et al. were probably the first to report that a single into-sciatic nerve or intrathecal injection of a lentiviral vector with a myelin-specific promoter resulted in targeted expression of connexin 32 in adult myelinating SCs throughout the PNS in Gjb1−/− mice, a genetically authentic model of CMT1X.