In the present study, no associations were detected between PDL1/Gal9 co-expression on blasts and age, sex, lymphadenopathy, hepatomegaly, splenomegaly, TLC, platelet count, PB blast percentage, Hb level in children or adults, BM cellularity, BM blast or lymphocyte percentages, IPT, CD34%, CD34+/CD38-%, CD4+/CD3 + or CD8+/CD3+% T-cell or the CD4/CD8 ratio. The gene discussed is CD4; the disease is Splenomegaly.