No associations were detected with age, gender, hepatomegaly, splenomegaly, lymphadenopathy, CNS involvement, Hb, TLC, platelets, PB and BM blasts percentages, BM cellularity, BM lymphocytes, IPT, CD4+/CD3+, CD8+/CD3+ % T-cells, the CD4/CD8 ratio, cytogenetic risk stratification, the DNA index, t(1;19), t(4;11), t(12;21), or t (9;22) p190. This evidence concerns the gene GSTM1 and Splenomegaly.