FASN and cancer: In rapidly proliferating tumor cells, lipid synthesis is reprogrammed to meet the increased demand for cell membrane components during cell division.[133] Key enzymes involved in lipid metabolism, such as fatty acid synthase (FASN) and acyl‐CoA synthetase, are often upregulated in various cancers, promoting the de novo synthesis of fatty acids and phospholipids.[134, 135, 136, 137] These lipids are vital not only for membrane structure but also for their role in cellular signaling pathways.