KRT88P and Hepatitis: The HBV core protein (HBc) plays a crucial role in HBV replication and has cytopathic effects associated with severe hepatitis, making it a promising therapeutic target for HBV infection and HBV infection related liver diseases.[5, 6] Once HBV pre‐genomic RNA (pgRNA) is transcribed from covalently closed circular DNA (cccDNA), HBc will be translated from pgRNA, and some HBc will be assembled into nucleocapsids.