Many of the DisGeNET disease terms that are significantly (corrected p-values < 0.05) enriched in genes selected by SMuGLasso (see S10 Table) correspond to subtypes of breast cancer (estrogen receptor-positive breast cancer, luminal A breast carcinoma, luminal B breast carcinoma, estrogen receptor-negative breast cancer, stage 0 breast carcinoma, mammary neoplasms). Here, ESR1 is linked to breast carcinoma.