Univariate analysis identified CLEC2D as well as pT, lymph node metastasis, histological grade, ER, PR, and Ki67 LI as significant prognostic factors for disease-free survival, while subsequent multivariate analysis revealed that pT (P = 0.012) and Ki67 LI (P = 0.0065) were independent prognostic factors for disease-free survival. The gene discussed is MKI67; the disease is metastatic malignant neoplasm in the lymph nodes.