Key immune-related pathways—such as ‘Complement and coagulation cascades’, ‘Cytokine–cytokine receptor interaction’, ‘IL-17 signaling pathway’, ‘Phagosome’, and ‘Rheumatoid arthritis’—were consistently enriched across both species, time points, and doses, highlighting a conserved inflammatory and immune activation profile (Figure 7). The gene discussed is IL17A; the disease is rheumatoid arthritis.