Compared with a previously published systematic review on the role of GLP‐1 RAs for headache and pain disorders, which included fewer studies (n = 2), a substantially smaller sample size (n = 54 IIH patients), and no GIP/GLP‐1 RA data, the present meta‐analysis provides an updated and more comprehensive synthesis, including pooled quantitative estimates from 1550 IIH patients [40]. The gene discussed is GCG; the disease is Pain.