Patients with early-onset T2DM had lower rates of postprandial glucose, Cr, BUN, eGFR levels, comorbid hypertension and coronary artery disease, and stroke than those with non-early-onset T2DM, and lower rates of late-onset CKM (P<0.05) (Table 1). The gene discussed is CKM; the disease is coronary artery disorder.