There have been various attempts to reduce the discrepancies between the second- and third-generation PTH assays in dialysis patients, by applying a correction factor or deriving an equation to allow interconversion between the two assays.31 A study by Wójtowicz et al. conducted in 2016 in Poland suggested the use of 1–84/7–84 PTH ratio to report PTH results to minimise potential misdiagnosis of CKD-BMD in CKD patients.31 However, further validation studies are needed, and these efforts are not currently adopted by clinical guidelines. This evidence concerns the gene PTH and chronic kidney disease.