ATG3 and liver cancer: Moreover, 5‐HT1BR signaling promotes autophagy and activates Notch signaling by upregulating the expression of light chain 3 (LC3) β and autophagy‐related effector proteins, such as elF4E‐binding protein 1 (4EBP1), autophagy related 3 (ATG3), Beclin1, and s65, thereby inducing liver cancer cell death [421].