CD4 and tuberculosis: Following the conclusion of phase 1 implementation of LAM testing in 28 facilities across four states in Nigeria, Anambra, Lagos, Akwa Ibom, and Rivers in February 2021, using the lessons learned, The Federal Ministry of Health (FMOH) adopted the use of LF-LAM as a point-of-care tests for the diagnosis of TB inpatients with AHD (cluster of differentiation 4 [CD4] count of 200 cells/mm3 and below) or the in the ‘seriously ill’ – unable to walk unaided, fever of 39 degrees, respiratory rate of 30 cycles/min and heart rate of 120 beats (i)/min5.