Similarly, western blotting showed that the protein expression levels of NLRP3, ASC, and cleaved caspase-1 were substantially increased in the wound tissues of the DM group compared with those in the control group (P < 0.05), whereas the expression levels of all these proteins were distinctly reduced in the DM + NaHS group (Figures 5D–F). This evidence concerns the gene NLRP3 and diabetes mellitus.