Centered on the structure of TRIM proteins, the outer circle presents related content from multiple dimensions: Key participants involved in gastric cancer, including PD-L1, EMT, and ncRNA, which play critical roles in processes such as gastric cancer oncogenesis and progression; TRIM protein-associated signaling pathways, such as the Wnt pathway, P53, and AKT. This evidence concerns the gene TRAT1 and gastric cancer.