A previous study reported that overexpression of TRIM14 promotes p-AKT, p-mTOR, and p-P70S6K expression, while TRIM14 knockout induces opposite effects; furthermore, AKT inhibition has been demonstrated to counteract the pro-migratory and pro-invasive effects of TRIM14 in gastric cancer cells (30). The gene discussed is TRIM14; the disease is gastric cancer.