NTRK1 and neoplasm: Targeted RNA sequencing was used to assess rearrangements involving a panel of 555 genes associated with tumorigenesis and tumor progression.A TPM3::NTRK1 gene fusion (NM_001043353.1/NM_002529.3) was detected in the tumor sample, with the specific fusion breakpoint located at exon 7 of TPM3 and exon 10 of NTRK1 (Figure 4B).