To investigate if ERK3 also modulates EMP in these types of cancer, we established stable cell lines of lung cancer A549 and pancreatic cancer MIA PaCa-2, with and without ERK3 knockdown, using the above-reported protocol, which were validated by Western blot (Supplementary Figures S5A, S6A). The gene discussed is MAEA; the disease is familial pancreatic carcinoma.