Similarly, in glioma cells overexpressing miR‐192, the expression of a stem cell marker (CD133) was obviously downregulated (2.653 ± 1.197 vs. 20.73 ± 1.235; *p < 0.05), whereas simultaneous high expression of EGR1 or HOXB9 partially increased the CD133 content (8.978 ± 0.215, 9.119 ± 0.578 vs. 2.653 ± 1.197; *p < 0.05). This evidence concerns the gene EGR1 and central nervous system cancer.