ART activates the transcription factor 4 (ATF4)/CEBP‐homologous protein (CHOP)/cation transport regulator‐like protein 1 (CHAC1) pathway and increases CHAC1 gene expression with γ‐glutamyl cyclotransferase activity, leading to decreased GSH levels and reduced antioxidant capacity of Burkitt's lymphoma cells [135]. The gene discussed is DDIT3; the disease is Burkitt lymphoma.