CD4 and infection: Among PWH, a significantly higher percentage of patients with prolonged mpox infections had a CD4 count <200 (10.0% [95% CI 3.33%–21.81%]; 5/50) or had no CD4 laboratory results available (46.0% [95% CI 31.81%–60.68%]; 23/50) compared with patients with nonprolonged infections, among whom only 3.9% (95% CI 3.24%–4.75%; 100/2,549) had a CD4 count <200 and 18.1% (95% CI 16.64%–19.63%; 461/2,549) had no CD4 laboratory results available.