CDK4 and head and neck squamous cell carcinoma: Second, we did not focus on the impact of CDK4/6i priming regimens on preventing lymphatic metastasis control, which frequently occurred in HNSCC patients.[41] Application of CDK4/6i priming regimens on an 4NQO‐induced carcinogenesis model in immunocompetent mice and analysis dynamic of draining lymph node (dLN) warrant further studies.