In both S. aureus-positive and S. chromogenes-positive cows, the DE snoRNAs were correlated with several immune and inflammatory genes (e.g., IL1R, IL18R1, STAT3, NFKB2, MYD88, VEGFA and CD40), all of which have been reported in several studies to be associated to mastitis [47–53]. The gene discussed is CD40; the disease is mastitis.