Meanwhile, inflammatory and immune pathways common to the S. chromogenes-positive and S. aureus-positive groups included NOD-like receptor signaling, NF-κB, TNF signaling, chemokine signaling, JAK-STAT signaling, and cancer pathways, while the common GO-BP terms with immune related functions included immune system processes, defense processes, and regulation of cytokine production etc. (Supplemental Table S6E, S5 F). The gene discussed is TNF; the disease is cancer.