Interestingly, neither Ube3amSTOP/p+ nor Vglut2-Cre::Ube3amSTOP/p+ mice showed a robust deficit in time spent in the center of the area, consistent with other studies demonstrating absent or weak anxiety-like phenotypes of AS model mice (Extended Data Fig. 3-2B; F(2,59) = 1.347, p = 0.2680; Born et al., 2017; Syding et al., 2022; Tanas et al., 2022). This evidence concerns the gene SLC17A6 and Anxiety.