The mean (SD) ataxia coefficient was significantly greater in the forelimbs (1.1 (1.0) vs 0.6 (0.5) p = 0.027), hindlimbs (0.9 (1.0) vs. 0.3 (0.2) p = 0.016), and all limbs (1.0 (1.0) vs. 0.3 (0.5) p = 0.015), of young M83+/− as compared to age-matched C57BL/6J control mice (Figure 8A). The gene discussed is PGAP6; the disease is Ataxia.