When flow cytometry data were expressed as MFI, the MFIs of mTOR, LC3I, LC3II, P62, CHOP, and GRP78 on CD4+ T lymphocytes were all significantly higher in elderly sepsis patients than in non-elderly sepsis patients (199.1 versus 139.2, P=0.026; 173.4 versus 103.8, P=0.023; 236.7 versus 123.5, P<0.001; 318.4 versus 192.5, P<0.001; 334.4 versus 164.2, P<0.001; 374.3 versus 218.6, P<0.001 respectively) (Table 2, Supplementary File S4). This evidence concerns the gene HSPA5 and Sepsis.