In the non-survived elderly sepsis patients, the percentages of CD4+ T lymphocytes expressing CHOP was markedly higher (98.2% versus 93.2%, P=0.021), and the percentage expressing LC3II, P62 and GRP78 was also slightly higher (87.0% versus 66.5%, P=0.128; 96.5% versus 95.7%, P=0.450 and 96.9% versus 86.8%, P=0.128 respectively). Here, HSPA5 is linked to Sepsis.