The MFIs of LC3II, P62, CHOP and GRP78 on CD4+ lymphocytes were also higher in the non-surviving sepsis patients (249.9 versus 134.8, P<0.001; 323.7 versus 200.6, P=0.002; 390.8 versus 177.6, P<0.001 and 389.1 versus 227.0, P<0.001) (Table 3, Supplementary File S5). The gene discussed is HSPA5; the disease is Sepsis.