Furthermore, TAMs regulate the epithelial-mesenchymal transition (EMT) process, affecting tumor metastasis, through the STAT/miR-506-3p/FoxQ1 signaling pathway and the TAT/miR-506-3p/FoxQ1 pathway, and promote the degradation of the extracellular matrix by secreting matrix metalloproteinases and C-C motif chemokine ligand 18 (CCL18). The gene discussed is CCL18; the disease is neoplasm.