Using the same bioinformatic methods, we uploaded SOX11 and 10 high myopia-related proteins (ERBB3, FGFR3, SOX4, COL9A1, COL2A1, COL11A1, ASXL1, COL18A1, P3H2 and P4HA2) to STRING database and generated a PPI network (Supplementary File S3), revealing that SOX11 has multiple interactions, including co-expression and experimentally determined interactions, with three high myopia-related proteins (COL9A1, COL2A1, and COL11A1), as well as protein sequence homology with another high myopia-related protein, SOX4. The gene discussed is PROS1; the disease is myopia.