GPT and diabetes mellitus: During an average follow-up of 5.0 ± 1.6 years, 315 (7.87%) MACE were recorded. Subjects who developed cardiovascular events were more likely to have intermediate or high LFSs, including NFS, fibrosis-4 score, body mass index, AST/ALT ratio, diabetes mellitus score, and AST/ALT ratio. Furthermore, compared with subjects with low scores, those with intermediate plus high score levels had a significantly increased risk of cardiovascular events (adjusted HR ranging 1.57–1.92)