The differentially expressed genes between the cardiomyocytesCSDC2 high subset and the cardiomyocytesCSDC2 low subset were mainly concentrated in processes related to myocardial remodeling, such as Cytoskeleton in muscle cells, Mitophagy—animal, Apelin signaling pathway, and Diabetic cardiomyopathy (Figure 8C). The gene discussed is APLN; the disease is diabetic cardiomyopathy.