However, it is crucial to acknowledge that results are not always consistent, as some research has shown no notable rise in BDNF levels after exercise in older adults with T2DM (Swift et al., 2012; Ghodrati et al., 2023; Silveira-Rodrigues et al., 2023a; Silveira-Rodrigues et al., 2023b). This evidence concerns the gene BDNF and type 2 diabetes mellitus.