ACHE and dementia: As such, AChE activity measurement is used in toxicity assessment and diagnosis of poisoning.26 Furthermore, biosensors that detect AChE inhibition have been developed for identifying residual pesticides and neurotoxic substances in the environment, and are being applied to food and water safety assessment.27,28 AChE is also a target in pharmaceutical development, and the measured activity is a fundamental and important parameter for the screening of new AChE inhibitors for dementia treatments or insecticides, as well as for structure–activity relationship studies.