Our differentials were ruled out due to the negative immunohistochemistry of NKX2.2, WT1, S-100, HMB-45, Desmin, and PanCK that ruled out Ewing sarcoma, CIC-DUX4 sarcoma, clear cell sarcoma of soft tissue, rhabdomyosarcoma, and synovial sarcoma, respectively [13]. The gene discussed is DES; the disease is Ewing sarcoma.