CDKN1A and Disorder of lipid metabolism: Lamas-Paz et al. (2025) discovered through data analysis from various patient cohorts and mouse models that the expression level of CDKN1A is significantly associated with non-alcoholic steatohepatitis (NASH), liver fibrosis, and more severe liver diseases such as cirrhosis and hepatocellular carcinoma, with its overexpression exacerbating lipid metabolic disorders and inflammatory responses.