Although GLUT1 and GLUT4 were thought to be responsible for cardiomyocyte glucose uptake [40], we were the first to show that SGLT1 protein is expressed in cardiomyocytes, and its expression is increased in diabetic cardiomyopathy, ischemia, and glycogen storage cardiomyopathy secondary to mutations in the gene encoding the γ2 subunit of AMP-activated protein kinase (AMPK) (PRKAG2) [4, 5]. Here, SLC5A1 is linked to diabetic cardiomyopathy.